1名55岁女性,因患2型糖尿病给予格列美脲2mg,1次/d早餐前0.5h口服。服药3d后,出现眩晕。经颅彩色多普勒超声(TCD)检查示:脑动脉硬化、椎-基底动脉供血不足。给予氟桂利嗪、地芬尼多、东莨菪碱抗眩晕治疗,但疗效欠佳。抗眩晕治疗3d后因血糖升高,格列美脲加量为4mg/次。服药1h后患者眩晕加重,伴恶心、呕吐,次日未能口服该药,眩晕当晚减轻,4d后消失。再次口服格列美脲4mg,1h后又出现眩晕,停用格列美脲28h后眩晕症状消失。 A 55-year-old female was given glimepiride 2 mg for type 2 diabetes once a day for 0.5 hours before breakfast. After taking medicine 3d, appear dizzy. Transcranial color Doppler ultrasound (TCD) examination showed: cerebral arteriosclerosis, vertebral - basilar artery insufficiency. Flunarizine, dendivudine, scopolamine anti-vertigo treatment, but poor efficacy. Anti-vertigo therapy after 3d due to elevated blood glucose, glimepiride dose of 4mg / time. 1h after taking patients with vertigo aggravated, with nausea, vomiting, the next day failed to take the drug, dizziness, reduced night, 4d disappear. Again glimepiride 4mg, 1h later appeared dizziness, glimepiride disabled 28h vertigo symptoms disappear.