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目的探讨两种方法治疗包裹性结核性胸腔积液的临床效果对比。方法将64例结核性包裹性胸腔积液患者,随机平分成2组,均给予常规抗结核治疗,治疗组置引流管后胸腔内注入尿激酶10万单位+0.9%氯化钠注射液50ml,对照组给予常规0.9%氯化钠注射液50ml胸穿抽液处理。结果对照组总有效率93.8%,治疗组全部有效,总有效率100%,两组差异相比无统计学意义(P>0.05)。治疗组退热的时间及胸腔积液吸收的时间短于对照组,但是差异无统计学意义(P>0.01),并发症发生差异也无统计学意义(P>0.01)。结论细管持续胸腔闭式引流加尿激酶反复注入治疗结核性胸腔积液安全、疗效显著,值得临床推广。
Objective To investigate the clinical effects of two methods in the treatment of tuberculous pleural effusion. Methods Sixty-four patients with tuberculous pleural effusion were randomly divided into two groups. All patients were given conventional antituberculous therapy. After the drainage tube of the treatment group, 50 ml of urokinase + 0.9% sodium chloride injection was injected into the thoracic cavity, The control group was given routine 0.9% sodium chloride injection 50ml thoracentesis treatment. Results The total effective rate was 93.8% in the control group. All the patients in the treatment group were effective and the total effective rate was 100%. There was no significant difference between the two groups (P> 0.05). The time of fever relief and pleural effusion absorption in the treatment group were shorter than that in the control group, but the difference was not statistically significant (P> 0.01). There was also no significant difference in complications between the two groups (P> 0.01). Conclusion Continuous thin-tube continuous thoracic drainage and urokinase infusion in the treatment of tuberculous pleural effusion, the effect is significant, worthy of clinical promotion.