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报导了氯铝酞菁（ＡｌＣｌＰｃ）在一定温度下直接磺化过程，反应时间对反应产物的影响．对磺化产物进行了元素分析、ＵＶ／ＶＩＳ、ＩＲ光谱表征，并利用逆相高效液相色谱（ＨＰＬＣ）进行分析和分离．分离得到的四磺基氯铝酞菁（ＡｌＣｌＰｃＴＳ）作为光敏剂对荷瘤鼠（Ｓ１８０）进行光动力治疗（ＰＤＴ）试验，结果表明抑瘤率可达８４．８４％．
The direct sulfonation of chloroaluminum phthalocyanine (AlClPc) at a certain temperature was reported, and the effect of reaction time on the reaction product was reported. The sulfonated products were characterized by elemental analysis, UV / VIS, IR spectroscopy and reverse phase high performance liquid chromatography (HPLC) for analysis and separation. The photodynamic therapy (PDT) test of the isolated tumor-bearing mice (S180) with the tetrasulfonyl chloroaluminum phthalocyanine (AlClPcTS) as the photosensitizer showed that the tumor inhibition rate was 84.84%.