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目的观察还原型谷光甘肽抢救治疗双硫仑样反应疗效及安全性。方法将我院2012年1月~2013年2月急救治疗的88例双硫仑反应患者,随机分为治疗组和对照组,治疗组用还原型谷光甘肽1200mg+生理盐水100ml静脉滴注;两组其它一般性基础治疗相同,观察用药后两组症状缓解快慢。结果治疗组缓解症状较对照组快,无明显副作用。结论还原型谷光甘肽抢救治疗双硫仑样反应见效快,不良反应少,安全可靠。
Objective To observe the efficacy and safety of reduced glutathione rescue treatment of disulfiram-like response. Methods Eighty-eight patients with disulfiram response to emergency treatment from January 2012 to February 2013 in our hospital were randomly divided into treatment group and control group. The treatment group received intravenous drip of reduced glutathione 1200mg and saline 100ml. Group of other general treatment of the same basic, observation of the two groups of symptoms after treatment, the speed of remission. Results The treatment group relieved symptoms faster than the control group, no obvious side effects. Conclusion The reduced glutathione rescue treatment of disulfiram-like response with quick, less adverse reactions, safe and reliable.