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2QN是一种直接从多刺链霉菌(Streptomycesechinatus)中由生物合成产生的喹喔啉抗生素棘霉素(echinomycin)的二喹啉衍生物。本文用DNase分子印迹法实验提供了一种研究2QN识别核苷酸序列的分子基础的起点。用PCR扩增合成了4种同源160bp酪氨酸胸苷(tyrT)DNA片段。每种都包含了天然
2QN is a quinoline derivative of the quinoxaline antibiotic echinomycin produced directly from the biosynthesis of Streptomyces septatus. In this paper, DNase molecular imprinting assay provides a starting point to study the molecular basis of 2QN recognition nucleotide sequence. Four homologous 160bp tyrT DNA fragments were synthesized by PCR. Each contains natural