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1990年9月～1991年12月治疗中晚期食管癌208例,随机分为综合组(放疗加卡铂)104例和单纯放疗组104例,两组照射方法相同~(60)CoD_T65～70Gy/6～7周。其1年生存率综合组80.8％,单纯放疗组55.8％,近期疗效判断前组明显优于后组,两组差异有统计学意义。综合组毒副反应高于单放组。
From September 1990 to December 1991, 208 patients with advanced esophageal cancer were randomly divided into comprehensive group (radiotherapy plus carboplatin) 104 cases and radiation alone group 104 cases. The two groups had the same irradiation method (60)CoD_T65~70Gy/ 6 to 7 weeks. The 1-year survival rate was 80.8% in the comprehensive group and 55.8% in the radiotherapy alone group. The short-term efficacy of the former group was significantly better than the latter group. The difference between the two groups was statistically significant. The comprehensive toxicity was higher than that of the radiotherapy group.