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本文通过277例慢性肝炎,重症肝炎的病理与临床对照观察,发现临床诊断与病理检查有较大差异。其中以CPH最为突出,47例CPH中仅有32例符合病理诊断,差异率高达32%,其它依次为亚急性重症(24%)、CAH重型(21%)、急性重症(20%)CAH(7%);部分病例在重复肝穿中发现有(28.5%)的CDH演变为CAH,有16.7%的CAH转化为CPH;发现CAH病例中,有无桥样坏死的病理学改变与它的演变有一定关系。在重病肝炎中,发现肝细胞残存率<30%病死率高达80%,而肝细胞残存率在30%—50%的病死率仅43.5%,有明显段差异。
In this paper, 277 cases of chronic hepatitis, severe hepatitis pathology and clinical control and found that there is a big difference between clinical diagnosis and pathological examination. Among them, CPH was the most prominent. Only 32 out of 47 cases of CPH were pathologically diagnosed, with a difference of 32%. The others were subacute severe (24%), CAH heavy (21%) and acute severe (20%) CAH 7%). In some cases, CDH evolved into CAH (28.5%) and CAH was converted into CPH (16.7%) in repeated liver puncture. The pathological changes of CAH with or without bridge-like necrosis and its evolution were found Have a certain relationship. Severe hepatitis, liver cell residual rate was found to be <30% fatality rate as high as 80%, while the liver cell residual rate of 30% -50% mortality was only 43.5%, there were significant differences.