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利多卡因快速静注可致心脏骤停,我院发生二例报告如下。例1:刘××,男,65岁,55kg,退休工人。心悸、气短一年,近半月加重,88年8月12日以冠心病、室性心律失常、心衰Ⅱ住院。既往有冠心病史。查体 Bp12.9/9.1Kpa(100/70mmHg)。神志清楚,呼吸平稳,体位自如。口唇及末稍轻度紫绀。颈静脉怒张。桶胸双肺底闻细小水泡音。心左界大,律不齐,5次/分早转,率94次/分,S_1略弱,无器质性杂音。肝肋下2.0cm,脾(一),下肢无水肿。ECG 示:窦性心律,频发多源室早,左室肥厚兼冠状动脉供血不足,V_1 ptf>0.04ms。x-D 两膈角少量积液,主 A 型心,左心大。入院后心电监护下以25%葡萄糖40ml 加入利多卡因80mg 静脉注射,2分内注入,即刻病人头晕、惊厥、烦躁,呼吸急促,继之心脏骤
Rapid intravenous lidocaine can cause cardiac arrest, two cases of our hospital as follows. Example 1: Liu × ×, male, 65 years old, 55kg, retired workers. Heart palpitations, shortness of breath year, nearly half of the increase, August 12, 88 to coronary heart disease, ventricular arrhythmia, heart failure Ⅱ hospitalization. Past history of coronary heart disease. Physical examination Bp12.9 / 9.1Kpa (100 / 70mmHg). Consciousness, breathing steady, comfortable position. Mild cyanosis lips and the end slightly. Jugular vein engorgement. Bottom of chest lungs smell small blisters sound. Left heart of the heart big, irregular, 5 times / min early turn, the rate of 94 beats / min, S_1 slightly weaker, no organic noise. Liver ribs 2.0cm, spleen (a), lower extremity no edema. ECG showed: sinus rhythm, frequent multi-source ventricular premature left ventricular hypertrophy and coronary insufficiency, V_1 ptf> 0.04ms. x-D two phrenic angle a small amount of effusion, the main A-type heart, left heart big. Admission under the ECG to 25% glucose 40ml add lidocaine 80mg intravenously, 2 minutes into the immediate patient dizziness, convulsions, irritability, shortness of breath, followed by cardiac arrest