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目的报道首例原发于肝脏的上皮-肌上皮癌患者。方法描述我院收治的1例经病理学明确诊断的肝脏原发的上皮-肌上皮癌的临床表现、影像学改变、病理特点等。患者女性,37岁,体检发现右肝直径10cm肿瘤,接受多项影像学(B超、CT、MRI)检查、反复肝脏穿刺活检和甲胎蛋白检查,但均无特异性,术前未能明确诊断。结果行右半肝切除,术后病理检查显示双套管样结构,免疫组化染色证实为上皮-肌上皮癌。结论该肿瘤在肝脏原发为罕见,术前诊断困难,需术后病理及免疫组化染色确诊。
Purpose To report the first case of primary epithelial-myoepithelial carcinoma in the liver. Methods Described in our hospital admitted to a case of pathologically confirmed liver primary epithelial-myoepithelial carcinoma clinical manifestations, imaging changes, pathological features. A 37-year-old female patient underwent physical examination with a 10-cm diameter tumor in the right liver and underwent multiple radiological examinations (B-mode, CT and MRI), repeated liver biopsy and alpha-fetoprotein examination, but none of them were specific diagnosis. The results of the right hemihepatectomy, postoperative pathology showed double-tube-like structure, immunohistochemistry confirmed epithelial-myoepithelial carcinoma. Conclusion The tumor is rare in the liver and its diagnosis is difficult before operation. Pathological and immunohistochemical staining is required.