论文部分内容阅读
根据WHO统计:育龄夫妇中约10％不能生育,其中与男性因素有关的约占50％。男性不育病人中绝大多数为不明原因性不育症,一般将其分为特发性无精子症、少精子症、弱精子症和畸形精子症。目前研究表明一部分不明原因性不育主要可能与染色体数目和结构异常或精子发生相关基因突变有关。前者常可出现异常症状及体征,如21三体、45,X等,而占较大比例的后者则常常为隐匿性,较不容易检出。如:Pryor等曾对12名Y染色体微缺
According to the WHO statistics, about 10% of couples of childbearing age can not give birth, of which about 50% are related to male factors. The vast majority of male infertility patients with unexplained infertility, generally divided into idiopathic azoospermia, oligozoospermia, asthenospermia and deformity sperm disease. The current study shows that some unexplained infertility may be mainly related to chromosome number and structural abnormalities or spermatogenesis-related gene mutations. The former can often appear abnormal symptoms and signs, such as 21 trisomy, 45, X, etc., while the latter is often a large proportion of occult, less easily detected. Such as: Pryor et al had 12 Y chromosome edema