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目的:通过对北京医院抗菌药物使用情况进行调查分析,为临床安全合理使用抗菌药物提供参考。方法:对2012―2015年抗菌药物的销售金额、用药频度(DDDs)和构成比,以及日均费用(DDC)等进行统计分析。结果:2012―2015年抗菌药物种类数呈现逐年下降的趋势,同时抗菌药物销售金额和DDDs虽然有所上升,但是占药品总销售金额的比例却逐年下降;4年中各类抗菌药物的用药金额和DDDs排序变化较小,销售金额大的品种相对固定,说明临床对常用抗菌药物的选择相对集中,其中头孢菌素类使用较多;绝大多数抗菌药物DDC持平或下调,同时使用频度高的药品相对来说DDC值较低。结论:北京医院对抗菌药物品种的选择和分级管理体现了有效性、安全性和多样性的特征,同时抗菌药物的使用较为合理,但也存在一些问题,需要改进。
OBJECTIVE: To investigate the use of antimicrobial agents in Beijing hospitals and provide references for the rational use of antimicrobial agents in clinical practice. Methods: Statistical analysis was conducted on the sales amount of antimicrobial drugs, the frequency of DDDs and composition, and the average daily cost (DDC) of antimicrobial agents during 2012-2015. Results: The number of antimicrobial agents showed a declining trend from 2012 to 2015, while the sales of antimicrobial drugs and DDDs increased year by year, but the proportion of the total sales of drugs dropped year by year. The amount of antimicrobial drugs And DDDs sort of change is relatively small, large amount of sales of the relatively large fixed species, indicating that the clinical choice of commonly used antimicrobial drugs are relatively concentrated, of which cephalosporins use more; most of the antimicrobial DDC flat or down, while the frequency of use The DDC value of the drug is relatively low. Conclusion: The selection and classification management of antibacterials in Beijing Hospital reflect the characteristics of effectiveness, safety and diversity. At the same time, the use of antibacterials is more reasonable, but there are some problems that need to be improved.