过敏原皮试在过敏性疾病诊断中已沿用了半个多世纪,这是一种简便、特异、敏感的方法。近十多年来,广泛开展了血清总IgE测定,但总IgE影响因素较多,如寄生虫感染常使血清总IgE水平显著增高,因此总IgE在过敏性疾病中并不是一种特异的临床指标。近年来国外使用RAST或ELISA测定特异性IgE,这为过敏性疾病提供了一种新的特异性诊断手段。我们在建立总IgE和特异性IgE测定方法的基础上,测定了一组蒿属(Artemisia)花粉症病人血清中总IgE和特异性IgE水平,并与皮试作 Allergen skin test has been used in the diagnosis of allergic diseases for more than half a century, which is a simple, specific and sensitive method. Over the past decade or so, the serum total IgE has been extensively tested, but there are many factors affecting total IgE. For example, parasitic infections often lead to a significant increase in serum total IgE levels. Therefore, total IgE is not a specific clinical condition in allergic diseases index. In recent years, the overseas use of RAST or ELISA for the determination of specific IgE, which provides a new and specific diagnostic tools for allergic diseases. Based on the establishment of total IgE and specific IgE assays, we measured the levels of total IgE and specific IgE in sera from a group of Artemisia hay fever patients and compared them with skin tests