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目的 :观察胸腺细胞腹腔注射佐治29例营养不良呼吸道感染患儿的临床效果及免疫功能。方法 :血清免疫球蛋白、SIL -2R、IL -2活性以及T淋巴细胞亚群分别采用快速免疫消浊比浊法 ,A PAAP、MTT以及ELISA法测定。结果 :与对照组比较 ,治疗前IL -2活性 ,CD3、CD4、和CD4/CD8 均明显降低(P<0.01) ,而SIL -2R则明显升高(P<0.01) ;治疗后 ,除SIL -2R明显降低(P<0.01)外 ,其余免疫学指标均明显升高(P<0.01) ,且临床治愈率82.76%明显高于对照组。结论 :胸腺细胞腹腔注射佐治营养不良合并反复呼吸道感染患儿有利于疾病康复
Objective: To observe the clinical effect and immune function of thymocytes in 29 children with malnourished respiratory tract infection by intraperitoneal injection. Methods: Serum immunoglobulin, SIL - 2R, IL - 2 activity and T lymphocyte subsets were measured by rapid immunoturbidimetric turbidimetry, A PAAP, MTT and ELISA respectively. Results: Compared with the control group, the levels of IL-2, CD3, CD4 and CD4 / CD8 were significantly decreased (P <0.01) and SIL-2R -2R decreased significantly (P <0.01), the other immunological parameters were significantly increased (P <0.01), and the clinical cure rate was 82.76% significantly higher than the control group. Conclusion: Thymic intraperitoneal injection of adjuvant treatment of malnutrition with recurrent respiratory tract infection in children is conducive to disease rehabilitation