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目的:研究酮替芬在哮喘治疗的临床应用价值。方法:选取本院自2013年2月~2015年2月间收治的130例哮喘患者,对其进行随机分组,分为对照组和观察组,每组65例患者,观察组采用酮替芬进行临床治疗,对照组则采用沙丁胺醇进行治疗,对比分析两组治疗效果。结果:经过本院统计学分析,观察组治疗总有效率为95.38%,对照组治疗总有效率为89.23%,观察组治疗总有效率明显高于对照组(P<0.05),具有统计学意义;患者症状缓解时间:观察组患者咳嗽缓解时间为(3.2±0.2)d、喘息缓解时间为(2.5±0.1)d、哮喘音缓解时间为(4.8±0.4)d、呼吸困难缓解时间为(2.3±0.5)d;对照组患者咳嗽缓解时间为(5.1±0.3)d、喘息缓解时间为(4.2±0.3)d、哮喘音缓解时间为(6.1±0.3)d、呼吸困难缓解时间为(4.7±0.6)d。则观察组的症状缓解时间明显短于对照组(P<0.05),具有统计学意义。结论:采用酮替芬治疗哮喘可以有效缩短症状缓解时间,并且其效果非常显著,值得临床的推广。
Objective: To study the clinical value of ketotifen in the treatment of asthma. Methods: A total of 130 asthmatic patients admitted to our hospital from February 2013 to February 2015 were randomly divided into control group and observation group, with 65 patients in each group. The observation group was treated with ketotifen Clinical treatment, the control group was treated with salbutamol, comparative analysis of two groups of treatment. Results: Through our hospital statistical analysis, the total effective rate of observation group was 95.38%, the total effective rate of control group was 89.23%, the total effective rate of observation group was significantly higher than that of control group (P <0.05), with statistical significance (3.2 ± 0.2) d, (2.5 ± 0.1) days for asthma relief, (4.8 ± 0.4) days for asthma relief, and 2.3 for relief of dyspnea ± 0.5) d. In the control group, the duration of cough relief was (5.1 ± 0.3) days, the duration of wheezing relief was (4.2 ± 0.3) days, the duration of asthma relief was (6.1 ± 0.3) days and the duration of dyspnea was 0.6) d. The symptom relief time of the observation group was significantly shorter than that of the control group (P <0.05), with statistical significance. Conclusion: The treatment of asthma with ketotifen can effectively shorten the time of symptom relief, and its effect is very significant, worthy of clinical promotion.