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近年来,口服头孢类抗生素的发展较为迅速,出现了一些引人注目的高效口服头孢类抗生素,打破了过去头孢类抗生素抗菌活性不强的局面,下面就口服头孢类抗生素的进展及有关品种进行评价。口服头孢类抗生素从头孢氨苄时代起,至目前的畅销药头孢克罗,除了给药量有所减少外,几乎无多大进展。其发展速度与注射用头孢类抗生素相比是相当缓慢的。结症所在是口服头孢类抗生素对体内酰胺酶的不稳定性及只具有中等抗菌活性,但由于给药方便,较少发生严重过敏反应,价格低于注射用等优点,以及近年来青霉素的变态反应和产
In recent years, the rapid development of oral cephalosporins antibiotics, there have been some high-profile oral cephalosporins antibiotics, cephalosporins antibiotics to break the past antibacterial activity is not strong situation, the following oral cephalosporins progress and related species Evaluation. Oral cephalosporins since the cephalexin era, to the current best-selling drug cefaclor, in addition to reducing the amount of medication, the almost no progress. Its rate of development is quite slow compared to injectable cephalosporins. Mycosis is oral cephalosporins antibiotics on the instability of amidase and only moderate antibacterial activity, but due to convenient administration, less serious allergic reactions, the price is lower than the advantages of injection, and penicillin metamorphosis in recent years Response and production