论文部分内容阅读
目的:研究临床常用静脉注射溶液在过滤前与过滤后不溶性微粒的数量与分布情况。方法:使用库尔特微粒计数分析仪对头孢拉定与环磷酰胺注射液在过滤前、过滤后不溶性微粒的数量与分布情况。结果:在过滤前。两种药品中的不溶性微粒的含量明显的超出了国家标准,过滤后不可溶性微粒直径>25μm的全部非过滤,颗粒滤除率100%,微粒直径在10~25μm之间的微粒滤除率为99.9%。结论:静脉注射药物时,使用过滤器将不溶性微粒过滤,能够有效降低不溶性微粒注入体内的数量。
Objective: To study the quantity and distribution of insoluble particles in clinical intravenous solution before and after filtration. Methods: The number and distribution of insoluble particulates after filtration were determined before and after filtration with cefradine and cyclophosphamide injection using the Coulter counter. Results: Before filtering. The content of insoluble particles in the two drugs significantly exceeded the national standard. The total non-filtered particle size of insoluble particles> 25μm after filtration, the particle filtration rate of 100% and the particle diameter of 10-25μm were 99.9%. Conclusion: The intravenous injection of drugs, the use of filters to filter insoluble particles, can effectively reduce the amount of insoluble particles injected into the body.