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目的筛选单纯疱疹病毒I型蛋白组中的PACS1结合蛋白。方法根据筛选标准,利用ScanProsite和PSORT软件对蛋白质进行分析,并结合相关文献中的实验数据对分析结果进行校正。结果该方法可有效地筛选出PACS1结合蛋白。利用该方法,在单纯疱疹病毒I型蛋白组中,共筛选出可能与PACS1结合的蛋白质33种。结论建立了一种有效的筛选PACS1结合蛋白的方法。筛选出的单纯疱疹病毒I型的PACS1结合蛋白,将为研究PACS1在疱疹病毒发生及潜伏性感染中的作用提供指导。
Objective To screen the herpes simplex virus type I protein PACS 1 binding protein. Methods According to the screening criteria, the proteins were analyzed by ScanProsite and PSORT software, and the results were corrected with the experimental data in the relevant literature. Results The method can effectively filter out the PACS 1 binding protein. Using this method, in the herpes simplex virus type I protein group, we screened out 33 possible proteins that may bind to PACS. Conclusion An effective screening method for PACS-1 binding protein was established. Screening out the herpes simplex virus type I PACS 1 binding protein, will provide guidance for the study of PACS 1 in herpes virus and latent infection.