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目的探讨非典型病原体感染与儿童哮喘的相关性研究。方法回顾性总结哮喘患儿90例临床资料设为观察组,根据一般资料类似原则搜集同期健康体检儿童40例资料设为对照组。结果观察组患儿体内CP-lgM阳性者20例(22.2%),CP-lgG阳性者18例(20%),MP-lgM阳性者10例(11.1%),明显高于对照组健康儿童感染情况(P<0.05);另外,病程<3个月的患儿CP感染率明显增大,患儿平均年龄与CP感染的persen相关系数为0.30(P<0.05),表现弱相关性。结论部分哮喘患儿的发病与CP感染密切相关,年龄较低的患儿因抗感染能力较低,更应重视对CP的预防。
Objective To investigate the correlation between atypical pathogen infection and childhood asthma. Methods The clinical data of 90 children with asthma were retrospectively defined as observation group. According to the similar principle of general data, 40 cases of healthy children in the same period were collected as control group. Results In observation group, 20 (22.2%) CP-lgM positive patients, 18 (20%) CP-lgG positive patients and 10 (11.1%) MP-lgM positive patients in observation group were significantly higher than those in healthy children (P <0.05). In addition, the CP infection rate in children younger than 3 months was significantly increased, and the persen correlation coefficient between the mean age and CP infection was 0.30 (P <0.05), showing a weak correlation. Conclusions The incidence of some asthmatic children is closely related to CP infection. The younger children have a lower anti-infective capacity and should pay more attention to the prevention of CP.