泪膜脂质层主要由睑板腺分泌的睑脂形成。脂质层具有重要的生理作用:(1)在瞬目过程中对眼睑运动起到润滑的作用;(2)阻止水液蒸发的屏障作用;(3)阻止微生物和有机物(如花粉)进入眼表~([1])。泪膜脂质层厚度变薄或脂质层成分改变,会使下方水液层蒸发加快,泪膜稳定性下降,泪液渗透压升高,进而引 The tear film lipid layer is mainly formed by the meibum secreted by meibomian glands. Lipid layers have an important physiological role: (1) they lubricate the eyelid during blinking; (2) prevent the water from evaporating; and (3) prevent the entry of microorganisms and organic matter (such as pollen) into the eye Table ~ ([1]). Film thickness thinning of the tear film or changes in the composition of the lipid layer will make the lower aqueous layer to evaporate faster, tear film stability decreased, tear osmotic pressure increased, and then cited