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目的分析晚期癌症难治性疼痛合并重度生存痛苦患者应用姑息性镇静治疗方案的临床价值。方法 2例晚期癌症难治性疼痛患者,应用镇静药物姑息治疗,监控患者生命体征,观察患者意识状态及生活质量,分析姑息性治疗临床意义。结果 2例晚期癌症患者均持续治疗至死亡,但患者及家属生活质量都有不同程度的提高。结论晚期癌症难治性疼痛患者出现重度生存困难,可通过姑息性镇静治疗方案缓解剧痛、恶心呕吐、腹胀等临床表现,安抚患者情绪,体现临终关怀,维护生命最后的尊严。
Objective To analyze the clinical value of palliative sedation in patients with advanced cancer refractory pain and severe survival pain. Methods Two patients with advanced cancer refractory pain were treated with sedative drug palliative therapy, the vital signs of patients were monitored, the patients’ consciousness status and quality of life were observed, and the clinical significance of palliative treatment was analyzed. Results Two patients with advanced cancer were treated to death, but the quality of life of patients and their relatives were improved to some extent. Conclusions Severe survival difficulties occur in patients with advanced cancer refractory pain. Palliative sedation can relieve the clinical manifestations of severe pain, nausea and vomiting, abdominal distension, appease the emotions of the patients, manifest the hospice and maintain the dignity of life.