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目的探讨胰岛素抵抗与脑卒中的关系。方法回顾性分析本院近年来收治的脑卒中患者胰岛素抵抗的临床资料,比较脑卒中各组与健康对照组FPG、FIns、ISI、C-P等指标的差异。结果急性期脑卒中各组的空腹血糖(FPG)、空腹血胰岛素(FIns)、C-肽(C-P)水平均明显高于健康对照组,而胰岛素敏感指数(ISI)与对照组比较明显降低,有极显著性差异,P<0.001。恢复期脑卒中各组的空腹血糖(FPG与健康对照组无差异性,P>0.05,空腹血胰岛素(FIns)、C-肽(C-P)水平、ISI与对照组比较有明显差异性。结论FPG、FIns、ISI、C-P等指标与脑卒中患者的病情及预后密切相关,故应重视脑卒中患者的胰岛素抵抗的治疗。
Objective To investigate the relationship between insulin resistance and stroke. Methods The clinical data of insulin resistance in stroke patients treated in our hospital in recent years were retrospectively analyzed. The differences of FPG, FIns, ISI and C-P between the groups of stroke and healthy controls were compared. Results The levels of fasting plasma glucose (FPG), fasting plasma insulin (FIns) and C-peptide (CP) in acute stroke group were significantly higher than those in healthy control group, while ISI decreased significantly compared with control group There was a significant difference, P <0.001. The fasting blood glucose in the recovery stroke group was significantly higher than that in the control group (there was no difference between the FPG group and healthy control group, P> 0.05, FIns, C-peptide, ISI) , FIns, ISI, CP and other indicators and stroke patients with the condition and prognosis are closely related, it should pay attention to the treatment of stroke in patients with insulin resistance.