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目的探讨影响桥本病与Graves病抗甲状腺药物(ATD)治疗的疗效。方法143例均为我院确诊,桥本甲亢68例,Graves病75例,年龄18～40岁,应用ATD治疗。结果经ATD治疗后,39.7%的桥本甲亢需持续用药;7.35%停药后出现甲减;Graves病缓解慢,复发率高,少数病人可出现自发性甲减。结论甲状腺大小,碘及TMAb,TGAb影响到ATD的治疗;停药后需定期监测甲功。
Objective To investigate the effect of Hashimoto’s disease and Graves’ disease on anti-thyroid drugs (ATD). Methods 143 cases were diagnosed in our hospital, Hashimoto Hyperthyroidism in 68 cases, 75 cases of Graves disease, aged 18 to 40 years, the application of ATD treatment. Results After ATD treatment, 39.7% of Hashimoto’s Hyperthyroidism need continuous medication; 7.35% after hypothyroidism, hypothyroidism; Graves disease slow response, high recurrence rate, a few patients may have spontaneous hypothyroidism. Conclusions Thyroid size, iodine and TMAb, TGAb affect the treatment of ATD; thyroid function should be monitored regularly after withdrawal.