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目的探讨脾弥漫性髓小B细胞淋巴瘤(SDRPSBCL)的临床病理特点、诊断和鉴别诊断。方法回顾性分析1例SDRPSBCL患者的临床病理资料,并结合相关文献进行复习。结果该例SDRPSBCL患者,以脾肿大、发热及淋巴细胞计数升高为主要表现,经脾脏组织病理学及其它相关检查确诊为SDRPSBCL。结论 SDRPSBCL是1种新被认识的独立疾病实体,临床少见,以中小淋巴瘤细胞弥漫性浸润脾脏红髓为重要病理特征。
Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of diffuse small marrow cell lymphoma of spleen (SDRPSBCL). Methods The clinical data of 1 SDRPSBCL patients were retrospectively reviewed and reviewed with related literatures. Results The patients with SDRPSBCL were mainly splenomegaly, fever and lymphocyte count increase. Their spleen histopathology and other related tests were confirmed as SDRPSBCL. Conclusion SDRPSBCL is a newly recognized independent disease entity. It is rarely seen clinically. It is an important pathological feature that diffuse infiltration of spleen red pulp into small lymphoma cells.