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目的探讨社区药学服务干预联合多药控制治疗对2型糖尿病患者的影响。方法选取上海市黄浦区打浦桥街道社区卫生服务中心2014年6月—2015年6月收治的2型糖尿病患者80例,按照随机数字表法将所有患者分为对照组和干预组,各40例。对照组患者给予多药控制治疗,干预组在对照组基础上联合社区药学服务干预。比较两组患者的血糖控制情况、自我管理行为情况(用药行为、生活方式、自我监测行为等)、药物不良反应(ADEs)发生情况。结果干预后,干预组患者血糖控制达标率高于对照组,空腹血糖(FPG)低于对照组(P<0.05)。干预组患者用药依从性、生活方式依从性、自我监测依从性评分高于对照组,ADEs发生率低于对照组(P<0.05)。结论采用社区药学服务干预联合多药控制治疗2型糖尿病疗效明显,可有效控制患者血糖及自我管理依从性,降低ADEs发生风险。
Objective To explore the impact of community pharmacy service intervention combined with multi-drug control on type 2 diabetes mellitus. Methods Eighty patients with type 2 diabetes mellitus were selected from Dapuqiao Street Community Health Service Center, Huangpu District, Shanghai from June 2014 to June 2015. All patients were divided into control group and intervention group according to random number table example. Patients in the control group were given multi-drug control treatment. The intervention group was combined with the community pharmacy service intervention on the basis of the control group. Blood glucose control, self-management behavior (medication behavior, lifestyle, self-monitoring behavior, etc.) and adverse drug reaction (ADEs) were compared between the two groups. Results After intervention, the rate of glycemic control in the intervention group was higher than that in the control group, and the fasting plasma glucose (FPG) was lower than that in the control group (P <0.05). The medication compliance, lifestyle compliance and self-monitoring compliance in the intervention group were higher than those in the control group, and the incidence of ADEs was lower than that in the control group (P <0.05). Conclusion The community pharmacy service intervention combined with multi-drug control in the treatment of type 2 diabetes has obvious curative effect, which can effectively control the patient’s blood sugar and self-management compliance and reduce the risk of ADEs.