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汀类药物作为羟甲基戊二酸单酰辅酶A还原酶抑制剂，在临床上被广泛应用于降脂及稳定动脉粥样硬化斑块，是急性心肌梗死和急性脑梗死治疗指南的推荐用药。除上述作用外，它还有非调脂性的保护作用，包括抗炎、抗氧化、改善内皮功能等。他汀类药物在降脂、稳定斑块的基础上，结合其非调脂性的保护机制，有助于减轻心肌梗死后心脏重构，降低心房颤动和室性心律失常的发生率，从而改善患者心功能，防止心源性猝死。“,”Statins as hydroxymethyl glutaryl coenzyme A ( HMG-CoA) reductase inhibitors,are widely used in the treatment of hyperlipidemia and atherosclerotic plaque stabilization ,and are recommended medi-cation by acute myocardial infarction and acute cerebral infarction treatment guidelines .In addition to the above effects, recent studies have shown that statins have noncholesterol-lowering effects including anti-inflammatory,antioxidation,improving endothelial function and so on.Combined with its noncholesterol-low-ering effects,statins can reduce the cardiac remodeling after myocardial infarction,prevent the occurrence of atrial fibrillation and ventricular arrhythmias,improve heart function and prevent sudden cardiac death.