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目的研究MP感染同支气管哮喘患者急性发作期具有的相关性,从而为临床治疗提供理论依据。方法对本院自2006年11月至2011年11月以来,于本科治疗的100例支气管哮喘的急性发作期患者(A组)与100例缓解期患者(B组)临床资料进行回顾性分析,检测其MP-IgM(外周血的支原体抗体)与IgE以及EOS(嗜酸粒细胞),并对比AB两组患者MP-IgM的阳性率以及上述三项指标的计数。结果 A组患者MP-IgM的阳性率为34.0%,B组为8.0%,两组相较,差异有统计学意义(P<0.01);其中MP-IgM呈阳性的患者IgE与EOS计数,同MP-IgM呈阴性的患者相较,差异有统计学意义(P<0.05)。结论 MP感染同支气管哮喘的急性发作具有密切的关系,急性发作期的支气管哮喘患者进行MP-IgM的常规检测,能够辅助临床诊疗。
Objective To study the correlation between MP infection and acute exacerbation of bronchial asthma in order to provide a theoretical basis for clinical treatment. Methods The clinical data of 100 patients with acute exacerbation of bronchial asthma (A group) and 100 patients with remission (B group) were retrospectively analyzed in our hospital from November 2006 to November 2011, The MP-IgM (peripheral blood mycoplasma antibody), IgE and EOS (eosinophils) were detected, and the positive rate of MP-IgM in the two groups was compared with that of the above three indexes. Results The positive rate of MP-IgM in group A was 34.0% and that in group B was 8.0%, there was significant difference between the two groups (P <0.01). IgE and EOS count in MP-IgM positive patients were the same The difference was statistically significant (P <0.05) in patients with negative MP-IgM. Conclusion MP infection is closely related to the acute attack of bronchial asthma. The routine examination of MP-IgM in patients with bronchial asthma during acute exacerbation can be used to assist clinical diagnosis and treatment.