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80年代中期以来,世界防治血吸虫病的中心措施已由控制中间宿主(灭螺)过渡为实施化疗,但影响人群化疗、限制和控制传播效果的主要因素是化疗后发生再感染。在日本血吸虫病,化疗后的再感染率很高。从防治决策的角度,研究可能指示人群易感状态的血清学指标具有重要的重论和实际意义,为构建预测性诊断试验,以指示人群感染和/或免疫状态提供理论依据。
Since the mid-1980s, the central measures for the prevention and control of schistosomiasis in the world have shifted from the control of intermediate hosts (molluscidae) to chemotherapy. However, the main factor affecting the population chemotherapy, limiting and controlling transmission is reinfection after chemotherapy. In Japan, schistosomiasis is highly re-infected after chemotherapy. From the perspective of prevention and treatment decision-making, it is of great importance and practical significance to study serological markers that may indicate population susceptibility, and provide a theoretical basis for constructing predictive diagnostic tests to indicate the population’s infection and / or immune status.