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目的:分析左氧氟沙星治疗耐多药肺结核的临床疗效,并对不良反应发生情况进行探究。方法:选取所在医院2014年8月-2016年11月68例耐多药肺结核患者,随机分组,对照组(n=34)患者采用常规疗法进行治疗,观察组(n=34)在此基础上给予左氧氟沙星,没对比2组患者患者临床疗效。结果:观察组临床总有效率(94.12%)、痰菌转阴率(97.05%)均高于对照组(73.53%、70.59%),组间存在显著差异(P<0.05);观察组治疗期间不良反应发生率(6.67%)低于对照组(23.33%),组间差异明显(P<0.05)。结论:左氧氟沙星治疗耐多药肺结核,可发挥良好的临床效果,具有临床应用价值。
Objective: To analyze the clinical efficacy of levofloxacin in the treatment of multidrug-resistant pulmonary tuberculosis (TB) and investigate the incidence of adverse reactions. Methods: Sixty-eight patients with MDR-TB in our hospital from August 2014 to November 2016 were selected and randomized. Patients in the control group (n = 34) were treated with conventional therapy. On the basis of this observation group (n = 34) Levofloxacin given, no comparison of two groups of patients with clinical efficacy. Results: The total effective rate (94.12%) and the negative conversion rate (97.05%) in the observation group were significantly higher than those in the control group (73.53%, 70.59%), with significant difference between the two groups (P <0.05) The incidence of adverse reactions (6.67%) was lower than that of the control group (23.33%), with significant difference between the two groups (P <0.05). Conclusion: Levofloxacin treatment of multidrug-resistant pulmonary tuberculosis, can play a good clinical effect, with clinical value.