三峡库区生态环境变化对血吸虫病流行的影响及防治对策研究

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目的研究三峡成库后生态环境变化对血吸虫病流行的影响,为制定防治方案提供科学依据。方法在三峡库区中段和尾端江岸海拔160m和180m高度,模拟成库后灌溉区和淤积区类似条件,投放湖北肋壳钉螺和四川光壳钉螺,观察其生长繁殖1年的情况;用IHA抽样筛查来往于疫区流动人群中潜在的传染源,粪便检查血吸虫虫卵;了解耕牛等生畜引进情况;调查重庆市历史疫情报告和三峡医院、重庆医科大学附属第一医院诊断的血吸虫病病例;调查影响钉螺输入的因素。结果肋壳钉螺和光壳钉螺成活率仅少数月份在50%以下,多数月份在80%左右,各试验区发现钉螺交配数量较少,相对以3~6月为多,同时发现活幼螺;来往疫区流动人员血清抗体检查1075人,血吸虫抗体阳性率为1.77%,疫区返乡人员1030人,血清阳性率为1.07%;1989-2006年,发现有记载的输入性血吸虫病病例14例;血吸虫病区有大量造纸原料和花草树木进入库区。结论三峡成库后,生态环境发生变化,存在血吸虫病流行的潜在危险。 Objective To study the impact of changes of ecological environment on the prevalence of schistosomiasis in the Three Gorges Reservoir, and provide a scientific basis for the formulation of prevention and treatment plans. Methods At the altitude of 160m and 180m in the middle and the tail bank of the Three Gorges Reservoir area, simulating the similar conditions in the irrigated and silted areas after the reservoir was established, the snail and the snail of Castanopsis kawakamii in Hubei Province were put into operation to observe the growth and reproduction for one year. Sampling and screening of potential source of infection in the floating population from the epidemic area, stool examination of schistosomiasis eggs; understand the introduction of cattle and other livestock; investigation of the historical reports of Chongqing City and the Three Gorges Hospital, Chongqing Medical University First Affiliated Hospital diagnosis of schistosomiasis Disease cases; investigate factors that affect snail input. Results The surviving rates of snail rib shell and light shell snail were only less than 50% in a few months and about 80% in most months. The number of snail mating was found less in each experimental area than in March to June, and the live snail was found at the same time. In the epidemic area, there were 1075 serological antibody tests of the floating population, 1.77% of the schistosoma antibody positive cases, 1030 returnees and seroprevalence of the epidemic area, with a positive rate of 1.7%. In 1989-2006, 14 cases of imported schistosomiasis were found. Schistosomiasis a large number of paper materials and flowers and trees into the reservoir area. Conclusion After the Three Gorges became a reservoir, the ecological environment changed and there was a potential danger of the epidemic of schistosomiasis.
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