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采用流式细胞技术研究了竹红菌甲素 (HA)对人Hce - 8693盲肠癌细胞周期、增殖活性的影响及在细胞凋亡中的诱导作用 ,结果 :HA主要使细胞阻断于G1期 ,G1期峰前出现典型的亚二倍体凋亡峰。提示 :HA具有诱导细胞凋亡及抑制肿瘤细胞增殖的作用。
Flow cytometry was used to study the effects of hypocrellin A (HA) on the cell cycle and proliferation of human Hce - 8693 cecal carcinoma cells and its induction in apoptosis. Results: HA mainly blocked cells in G1 phase , Typical sub-diploid apoptotic peak appeared before G1 peak. Tip: HA has the role of inducing apoptosis and inhibiting tumor cell proliferation.