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为了解高原乏氧及铁缺乏对儿童身心发育的影响,对195例亚高原和233例高原城区儿童进行体格发育、智能发育筛查(DDST)、红细胞内游离原卟啉(FEP)及血红蛋白(Hb)等调查和对照研究。结果显示:(1)两组儿童体重和身高Z分较平原参照人群(1985年中国九市城区儿童)呈不同程度降低,其中以身高Z分的降低更为显著,随年龄段升高亚高原组两Z分逐渐向参照人群靠近,而高原组无此趋势。(2)FEP与儿童身高Z分呈负相关,DDST结果异常或可疑者FEP水平高于正常者。(3)本文高原组FEP水平及贫血患病率明显高于亚高原组,其随年龄的变化在两组间亦有差异。提示:高原乏氧和铁缺乏对儿童发育的不利影响,本文资料示随海拔升高而趋于明显。因此,对不同海拔地区儿童采取相应的保健措施,重视对铁缺乏的防治,是促进高原儿童身心发育的重要手段。
In order to understand the effect of plateau hypoxia and iron deficiency on physical and mental development of children, physical fitness, intelligent developmental screening (DDST), erythrocytic free protoporphyrin (FEP) and hemoglobin Hb) and other survey and control studies. The results showed that: (1) The body weight and height Z scores of children in both groups were lower than those in the plain reference population (children in Jiucheng, China in 1985), with the Z-height reduction being more significant, with the age-increasing sub-plateau Group Z points gradually approaching the reference group, while the plateau group no such trend. (2) FEP was negatively correlated with children’s height Z score, abnormal DDST results or suspicious FEP levels were higher than normal. (3) The plateau group FEP level and the prevalence of anemia were significantly higher than the sub-plateau group, with its age changes in the two groups also have differences. Hint: The adverse effects of hypoxia and iron deficiency on the development of children in the plateau are evident with the elevation of the data presented here. Therefore, it is an important measure to promote the physical and mental development of plateau children by adopting appropriate health care measures for children at different altitudes, paying attention to the prevention and treatment of iron deficiency.