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用核酸电泳法对1983～1987年秋、冬季收集的318份急性腹泻患儿的粪便标本进行了轮状病毒的分子流行病学研究,阳性187份。研究表明,轮状病毒始终是本地区秋、冬季节婴幼儿急性腹泻的病原体。轮状病毒的RNA 电泳型分析提示,5年中本地区一直系长型毒株(笫Ⅱ亚群)为流行的优势株,其中4年同时伴有短型毒株(第Ⅰ亚群)流行。从187份阳性标本中检出差异型21个。4个属短型,17个属长型。每年都有数个电泳型毒株流行,但仅有其中的一个占流行优势。多数毒株仅流行1～2年,但有2个毒株持续4～5年被检出。提示轮状病毒的基因组有一定稳定性。
The molecular epidemiology of rotavirus in 187 stool samples collected from 1983 to 1987 in autumn and winter collected from children with acute diarrhea was analyzed by electrophoresis. Studies have shown that rotavirus is always the pathogens of acute diarrhea in infants and young children in autumn and winter in this area. Rotavirus RNA electrophoresis analysis showed that in the past five years, there has been a dominant strain in this area (Zi Ⅱ subpopulation), of which 4 years were accompanied by the prevalence of the short strain (subgroup Ⅰ) . A total of 21 differential samples were detected from 187 positive samples. 4 are short, 17 are long. Several electrophoresis strains are prevalent every year, but only one of them is prevalent. Most strains were prevalent for 1 to 2 years, but 2 strains were detected for 4-5 years. Suggesting that the genome of rotavirus has some stability.