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目的 探讨单纯性肥胖对肾脏功能的损伤。 方法 ＲＩＡ 检测７１ 例单纯性肥胖儿童２４ 小时尿中微量ＡＩｂ 、ＩｇＧ、β２ － Ｍ 及ＴＨＰ 的含量。 结果 ７１ 例肥胖儿童尿中ＡＩｂ 含量分别与ＢＭＩ、收缩压及血清胆固醇呈显著正相关。 结论 肥胖引起的肾功能早期改变使尿ＡＩｂ 、ＩｇＧ 排泄量增加。
Objective To investigate the effect of simple obesity on renal function. Methods RIA was used to detect the levels of trace AIb, IgG, β2 - M and THP in 24 hours urine of 71 simple obese children. Results The urinary AIb levels in 71 obese children were positively correlated with BMI, systolic blood pressure and serum cholesterol, respectively. Conclusion Early changes of renal function induced by obesity increase the excretion of urine AIb and IgG.