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目的比较介入治疗与药物保守治疗对急性心肌梗死患者长期疗效的影响。方法从2015年12月至2016年12月登封市人民医院接受治疗的急性心肌梗死患者中随机选取64例进行研究,并将其分为对照组与实验组,均为32例。予以对照组实施常规药物治疗,实验组实施经皮冠状动脉介入疗法(PCI)治疗,对比两组患者血浆NT-pro BNP含量、心电图各项指标及后期存活情况。结果治疗后24 h与48 h,实验组血浆NT-pro BNP含量下降幅度优于对照组,含量值均低于对照组,且P<0.05,差异具有统计学意义。两组患者左室舒张末期内径、与收缩末期内径均明显下降,左心室射血分数均有所提升,但两者差异无明显统计学意义,P>0.05。对照组死亡率(28.12%)高于实验组(6.25%),且P<0.05,差异具有统计学意义。结论采用经皮冠状动脉介入疗法对急性心肌梗死患者实施治疗,可明显改善降低血浆NT-pro BNP含量,降低死亡率,临床疗效显著。
Objective To compare the long-term effects of interventional therapy and conservative treatment on patients with acute myocardial infarction. Methods From December 2015 to December 2016 Dengfeng People’s Hospital of patients with acute myocardial infarction were randomly selected 64 cases were studied and divided into control group and experimental group, were 32 cases. The control group was treated with conventional drugs. The experimental group was treated with percutaneous coronary intervention (PCI). The levels of plasma NT-pro BNP, electrocardiogram indexes and post-survival were compared between the two groups. Results The levels of plasma NT-pro BNP in experimental group were significantly lower than those in control group at 24 h and 48 h after treatment, both of which were lower than those of control group (P <0.05). The difference was statistically significant. Left ventricular end-diastolic diameter and end-systolic diameter of both groups were significantly decreased and left ventricular ejection fraction increased, but there was no significant difference between the two groups (P> 0.05). The mortality of the control group (28.12%) was higher than that of the experimental group (6.25%), P <0.05, the difference was statistically significant. Conclusion The percutaneous coronary intervention in patients with acute myocardial infarction in the treatment, can significantly reduce plasma NT-pro BNP levels, reduce mortality, a significant clinical effect.