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目的:观察中医辨证联合圣·约翰草提取物治疗肠易激综合征(IBS)的临床疗效。方法:将134例IBS患者分为两组,对照组(82例)采用中医辨证治疗,治疗组(52例)在中医辨证治疗基础上联合圣.约翰草提取物治疗。结果:总有效率治疗组85.71%,对照组46.15%,治疗组疗效明显高于对照组(P<0.01),且两组同型疗效相比,均有显著性差异(P<0.01),但治疗组腹泻型IBS和便秘型IBS的疗效高于腹泻便秘交替型IBS患者(P<0.01)。结论:中医辨证联合圣.约翰草提取物治疗肠易激综合征效果较好,尤适用于腹泻型和便秘型患者。
Objective: To observe the clinical effect of syndrome differentiation combined with St. John’s wort extract in treating irritable bowel syndrome (IBS). Methods: 134 IBS patients were divided into two groups. The control group (82 cases) was treated with TCM syndrome differentiation. The treatment group (52 cases) was treated with St. John’s wort extract on the basis of TCM syndrome differentiation. Results: The total effective rate was 85.71% in the treatment group and 46.15% in the control group, and the curative effect in the treatment group was significantly higher than that in the control group (P <0.01). There was significant difference between the two groups in the same type of curative effect (P <0.01) The efficacy of diarrhea IBS and constipation IBS was higher than that of diarrhea constipation alternating IBS patients (P <0.01). Conclusion: Syndrome Differentiation combined with St. John’s wort extract treatment of irritable bowel syndrome is better, especially for diarrhea and constipation patients.