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目的:观察短期胰岛素强化治疗初发2型糖尿病的临床疗效及安全性。方法:选择近年来诊治的102例初发2型糖尿病患者,随机分为短期胰岛素强化治疗组和常规治疗组,两组患者均给予控制饮食和体育锻炼。结果:胰岛素强化治疗组的糖化血红蛋白及Homa-IR显著优于对照组,两组患者的并发症发生情况无明显差异。结论:采用短期胰岛素强化治疗初发2型糖尿病具有临床疗效好,依从性高,安全性高等优点,值得临床进一步研究使用。
Objective: To observe the clinical efficacy and safety of short-term intensive insulin treatment of type 2 diabetes. Methods: A total of 102 patients with newly diagnosed type 2 diabetes who were diagnosed and treated in recent years were randomly divided into short-term intensive insulin treatment group and conventional treatment group. Both groups were given diet and physical exercise. Results: HbA1c and Homa-IR in the intensive insulin treatment group were significantly better than those in the control group. There was no significant difference in the complication between the two groups. Conclusion: Short-term intensive insulin treatment of type 2 diabetes mellitus has the advantages of good clinical efficacy, high compliance and high safety. It is worth further clinical study.