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目的:观察分析左卡尼汀联合无创通气治疗慢性阻塞性肺疾病(COPD)并慢性呼吸衰竭的临床效果。方法:选取本院2013年2月-2014年10月收治的COPD并慢性呼吸衰竭患者90例,将其随机分为对照组与观察组,对照组患者在常规治疗的基础上使用无创通气进行治疗,观察组患者在对照组患者的治疗基础上使用左卡尼汀联合无创各45例通气进行治疗,对两组患者的临床治疗效果进行分析比较。结果:观察组住院7 d及14 d的缓解率分别是82.22%、95.55%与对照组的66.66%、86.66%相比,差异具有统计学意义(P<0.05);观察组患者再住院率、死亡率等情况与对照组相比,差异具有统计学意义(P<0.05);两组患者治疗1年后,观察组患者气血指标明显优于对照组,(P<0.05)。结论:使用左卡尼汀联合无创通气治疗COPD并慢性呼吸衰竭患者,治疗效果明显。
Objective: To observe and analyze the clinical effect of levocarnitine combined with non-invasive ventilation in treating chronic obstructive pulmonary disease (COPD) and chronic respiratory failure. Methods: Ninety patients with COPD and chronic respiratory failure who were admitted to our hospital from February 2013 to October 2014 were randomly divided into control group and observation group. Patients in control group were treated with non-invasive ventilation on the basis of routine treatment The patients in the observation group were treated with levocarnitine and noninvasive 45 cases of ventilation on the basis of the treatment of the control group, and the clinical effects of the two groups were analyzed and compared. Results: The remission rates of observation group on day 7 and day 14 were 82.22% and 95.55%, respectively, compared with 66.66% and 86.66% of control group (P <0.05). The rehospitalization rate, (P <0.05). After one year of treatment, the blood gas indexes of the observation group were obviously better than those of the control group (P <0.05). Conclusion: L-carnitine combined with noninvasive ventilation in patients with COPD and chronic respiratory failure, the treatment effect is obvious.