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目的探讨膀胱肿瘤手术中采用丝裂霉素注射肿瘤基底部的意义及疗效。方法全部病例共113人,分为试验组和对照组。其中试验组59人,对照组54人,选取对象全部采取开放性手术切除方法 ,手术方式大致相同,试验组术中采用丝裂霉素作肿瘤基底部注射后作肿瘤切除。对照组作单纯手术切除。结果手术成功,术后均做膀胱灌注治疗,随访试验组复发9例,对照组复发17例。统计学处理采用χ2检验方法得出两组之间术后复发率有显著性差异。结论采用丝裂霉素作膀胱肿瘤基底部注射后手术能降低患者手术后肿瘤的复发率。
Objective To investigate the significance and efficacy of mitomycin injection in the tumor base of bladder tumor. Methods A total of 113 cases of all cases, divided into experimental group and control group. 59 patients in the test group and 54 in the control group. All the patients were treated by open surgical resection. The operation methods were roughly the same. Mitomycin was used in the experimental group for tumor resection after injection. Control group for simple surgical resection. Results The operation was successful. The patients were treated with bladder irrigation after operation. Nine patients recurred in the trial group and 17 in the control group. Statistical analysis using χ2 test showed that there was a significant difference between the two groups in the recurrence rate. Conclusion Mitomycin can be used to reduce the recurrence rate of tumor after operation in patients with bladder tumor.