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探讨SPECT腮腺功能测定评价鼻咽癌患者不同设野放射治疗后腮腺功能损伤情况的可行性 材料和方法:选取40例鼻咽癌患者作研究对象,行单纯放射治疗,其中23例行双耳前野放疗,17例行双耳前野加鼻前野放疗。患者在放疗前和放疗后均用SPECT检测其腮腺功能 结果:常规鼻咽双耳前野加鼻前野放射治疗和双耳前野放射治疗的腮腺摄取功能极度损伤率分别为5.9％(2/34)和28.3％(13/46);排泌功能极度损伤率分别为23.5％(8/34)和56.5％(26/46),两对照组比较均有统计学差异(P<0.05)。结论:SPECT腮腺功能测定是评价鼻咽癌患者放射治疗后腮腺功能损伤程度的敏感、适用的方法,腮腺损伤以排泌功能损伤为主,放射剂量愈人,腮腺的摄取和排泌功能损伤愈严重。
To investigate the feasibility of SPECT parotid gland function evaluation of nasopharyngeal carcinoma patients with different field radiation after parotid gland function of the feasibility of materials and methods: 40 cases of nasopharyngeal carcinoma patients selected for study, the simple radiotherapy, of which 23 cases of the former Radiotherapy, 17 cases of prefrontal plus nasal anterior field radiotherapy. The patients were examined by SPECT before and after radiotherapy for parotid function. The results showed that parotid gland function was significantly reduced in 5.9% (2/34) and 28.3% (13/46). The excretion function extremity injury rates were 23.5% (8/34) and 56.5% (26/46), respectively. There were significant differences between two control groups (P <0.05). Conclusion: SPECT parotid gland function test is a sensitive and applicable method to evaluate the degree of parotid gland function after radiotherapy in patients with nasopharyngeal carcinoma. Parotid gland injury is characterized mainly by excretory function damage, radiation dose is more, the uptake and excretion of the parotid gland are more damaged serious.