论文部分内容阅读
目的介绍并讨论阑尾杯状细胞类癌的临床病理特征、生物学行为及鉴别诊断。方法结合免疫组化分析1例阑尾杯状细胞类癌。结果癌细胞小腺泡样、小团状或条索状排列浸润性生长于阑尾壁全层。免疫组织化学标记Syn、CD56、NSE、CK8/18均为阳性,CgA阴性,Ki-67阳性约5%。结论阑尾杯状细胞类癌是一种在组织学形态及免疫表型上具有类癌和腺癌双向分化的低度恶性肿瘤,经阑尾切除术结合右半结肠切除预后良好。
Objective To introduce and discuss the clinicopathological features, biological behavior and differential diagnosis of appendiceular goiter carcinoid. Methods One case of appendiceular goiter carcinoid was analyzed by immunohistochemistry. The results of small acinar cancer cells, small clusters or cord-like infiltration of invasive growth in the full thickness of the appendix wall. Immunohistochemical markers Syn, CD56, NSE, CK8 / 18 were positive, CgA negative, Ki-67 positive about 5%. Conclusions The appendix goblet cell carcinoid is a low-grade malignant tumor with bi-directional carcinoid and adenocarcinoma histology and immunophenotyping. The prognosis is good with appendectomy and right-sided colon resection.