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目的分析甲泼尼龙联合阿奇霉素治疗小儿难治性支原体肺炎的临床效果。方法 60例小儿难治性支原体肺炎患儿,随机分为观察组和对照组,各30例。两组患儿均行纠正酸碱平衡紊乱和常规吸氧及静脉滴注阿奇霉素治疗,观察组在此基础上加入甲泼尼龙进行治疗,比较两组患儿的治疗效果。结果观察组患儿体温恢复时间、住院时间、治疗后1周C反应蛋白水平均优于对照组,差异均有统计学意义(P<0.05)。结论在小儿难治性支原体肺炎的临床治疗中,采用甲泼尼龙联合阿奇霉素进行治疗能够有效缩短患儿的体温恢复时间和住院时间,临床效果显著,临床可推广应用。
Objective To analyze the clinical effect of methylprednisolone and azithromycin in the treatment of refractory mycoplasma pneumonia in children. Methods Sixty children with refractory mycoplasma pneumonia were randomly divided into observation group (n = 30) and control group (n = 30). Both groups were corrected for acid-base balance disorders and conventional oxygen and intravenous azithromycin treatment, the observation group on the basis of methylprednisolone treatment, the treatment of children in both groups were compared. Results The body temperature recovery time, hospitalization time and the level of C-reactive protein in the observation group were better than those in the control group (P <0.05). Conclusion In the clinical treatment of refractory mycoplasma pneumonia in children, the use of methylprednisolone combined with azithromycin can effectively shorten the recovery time and hospital stay in children with significant clinical effect, the clinical application can be promoted.