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目的观察神经阻滞联合普瑞巴林治疗带状疱疹后遗神经痛的临床疗效。方法选择带状疱疹后遗神经痛患者60例随机分为A、B、C三组,分别采用普瑞巴林治疗、神经阻滞治疗、神经阻滞联合普瑞巴林治疗,使用视觉模拟评分评价疼痛的缓解,评价疗效。结果三组患者治疗后1、2、3、4周VSA评分均为显著降低(P<0.01),但A、B两组的VSA评分与C组相比较低,其差异具有统计学意义(P<0.05),同一时间段C组的优良率明显高于A组和B组。结论神经阻滞联合普瑞巴林治疗带状疱疹后遗神经痛较单独使用普瑞巴林和单独采用神经阻滞治疗效果好,值得临床推广。
Objective To observe the clinical efficacy of nerve block combined with pregabalin in the treatment of postherpetic neuralgia. Methods Sixty patients with postherpetic neuralgia were randomly divided into three groups: A, B and C, treated with pregabalin, nerve block, and nerve block combined with pregabalin respectively. The visual analog scale was used to evaluate the pain Ease, evaluate the curative effect. Results The VSA scores of the three groups were significantly decreased at 1, 2, 3 and 4 weeks after treatment (P <0.01), but the VSA scores of A and B groups were lower than those of C group (P <0.05). In the same time period, the excellent and good rates of C group were significantly higher than those of A and B groups. Conclusion Nerve block combined with pregabalin in the treatment of postherpetic neuralgia is better than pregabalin alone and nerve block alone, which is worthy of clinical promotion.