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[目的]探讨急性超容血液稀释在小儿手术中的应用。[方法]将30例ASAI～II级拟行大中型手术的小儿随机分为两组:对照组和治疗组。麻醉后治疗组实施急性超容血液稀释,而对照组则按常规处理。监测术中MAP、CVP、动脉血气、电解质、Hb、尿量和手术出血量、输血量。[结果]治疗组急性超容血液稀释后Hb显著降低,且显著低于对照组(P﹤0.05);治疗组术毕及术后1d显著高于对照组(P﹤0.05);两组出血量差异无统计学意义(P﹥0.05),但输血量治疗组显著低于对照组(P﹤0.05);术中MAP、CVP、动脉血气、电解质和尿量均正常,两组比较差异无统计学意义(P﹥0.05)。[结论]急性超容血液稀释用于小儿手术是安全有效的。
[Objective] To investigate the application of acute hypercapnia hemodilution in pediatric surgery. [Methods] Thirty ASAS II children were randomly divided into two groups: control group and treatment group. After anesthesia, the patients in treatment group were given acute hypervolemic hemodilution while those in control group were routinely treated. Monitoring intraoperative MAP, CVP, arterial blood gas, electrolytes, Hb, urine output and blood loss, blood transfusion. [Results] The Hb in the treatment group after acute hypervolemic hemodilution was significantly lower than that in the control group (P <0.05). The treatment group was significantly higher than the control group (P <0.05) There was no significant difference between the two groups (P> 0.05), but the blood transfusion volume was significantly lower in the treatment group than in the control group (P <0.05). MAP, CVP, arterial blood gas, electrolytes and urine volume were normal in the two groups Significance (P> 0.05). [Conclusion] Acute hypervolemic hemodilution is safe and effective for pediatric surgery.