近年来,体内传统DC(cDC),尤其是黏膜表面或淋巴器官的DC,能否不依赖骨髓发生,而从外周直接分化产生,已成为科学家们争论的热点。研究发现,病灶局部和引流淋巴结的DC数量显著增加是机体炎症反应的重要特征,那么炎症反应中大量DC来源于何处?这一问题一直令人困惑。论文作者通过复 In recent years, the traditional DC (cDC) in vivo, especially the mucosal surface or lymphoid organs of the DC, can be independent of bone marrow, but the direct differentiation from the periphery has become a hot debate scientists. The study found that a significant increase in the number of DCs in the focal and draining lymph nodes is an important feature of the inflammatory response in the body. Where is the bulk of the DCs from the inflammatory response? This has been a matter of confusion. The author through the complex