目的探讨功能性消化不良(FD)的病因,比较药物与精神心理疏导的临床反应。方法对300例FD门诊病人,从精神心理指导(启发开导和精神支持)、生活指导(生活饮食习惯)及药物治疗(安定、多虑平、西沙必利、法莫替丁、抗幽门螺杆菌药物)三方面观察,比较其疗效。结果治愈200例(66%),好转42例(14%),未愈58例(19.3%),总有效率80%。结论FD是具有上腹部症状而无局部和全身器质性疾病证据的临床综合征,治疗上应重在精神心理指导,药物治疗宜简单,抗焦虑、抑郁及促胃动力药物对多数患者有效,无需追求新药贵药。 Objective To investigate the etiology of functional dyspepsia (FD) and to compare the clinical response of drug and psychosocial evacuation. Methods A total of 300 outpatients with FD were enrolled in this study. They included psychiatric guidance (inspired enlightenment and mental support), life guidance (lifestyle and diet) and medication (diazepam, doxepin, cisapride, famotidine, Drugs) three aspects of observation, compare its efficacy. Results 200 cases (66%) were cured, 42 cases (14%) were improved, 58 cases (19.3%) were cured and the total effective rate was 80%. Conclusion FD is a clinical syndrome with evidence of upper abdomen without local and systemic organic disease. Treatment should focus on mental and psychological guidance. Drug therapy should be simple, anti-anxiety, depression and gastric motility drugs are effective in most patients, No need to pursue new drugs expensive medicine.