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紫花洋地黄叶(Digitalis purpura L.)內含有多种强心甙类,是一种重要的强心药物。把它磨成粉,加入适量的水(約1:1),在20—25℃的溫度下放置24小时进行醱酵水解后,用有机溶煤提取,去掉能用的杂质,即可得到强心甙类——洋地黄毒甙(Digitoxin C_(41)H_(64)O_(13))、吉妥辛(Gitoxin C_(41)H_(64)O_(14))、吉他林(Gitalin C_(35)H_(56)O_(12))等。其中洋地黃毒甙佔总量的50%左右。据文献記載,它們的水解产物——地芰配醣基、芰毒配醣基等,同样也具有强心疗效。由此可見,紫花洋地黄叶内的各有效成份包括各种甙类以及它們的水解产物配醣基,均具有强心疗效,因此可以作为綜合利用的对象。而目前有些生产單位仅从紫花洋地黄叶中提取洋地黄毒甙一种产品,把其他的有效强心成分却当作廢物棄去,实为可惜。为适应国家工农業生产大跃进的形势,做到物尽其用,我厂根据洋地黄毒甙生产工艺过程的特点,綜合利用了洋地黄毒甙生产中的各种副产品,生产出新地加林、洋地黄酊、叶绿素等产品。現將有关生产方法及經驗介紹于下:
Purpleis purpura L. contains a variety of cardiac glycosides and is an important cardiac drug. Grind it into powder, add appropriate amount of water (about 1:1), place it at 20-25°C for 24 hours to ferment the fermented yeast, and extract it with organic coal, remove the usable impurities, and get strong Cardioplegia: Digitoxin C_(41)H_(64)O_(13)), Gitoxin C_(41)H_(64)O_(14), Guitar Gin (Gitalin C_ 35) H_(56)O_(12)) and so on. Among them, digoxigenin accounts for about 50% of the total. According to the literature, their hydrolyzed products, such as glycosides and glycosides, also have strong cardiac effects. It can be seen that the effective components in the purple leaves of Viola yedoensis include various terpenoids and their hydrolysates and glycosyl radicals, all of which have strong cardiac effects, and therefore can be used as objects of comprehensive utilization. At present, some production units only extract a product of digoxigenin from the yellow leaves of purple flowers, and it is a pity that other effective ingredients are discarded as waste. In order to adapt to the great leap forward of the industrial and agricultural production of the country and to make the best use of it, our factory has comprehensively used various by-products from the production of digoxigenin to produce new ground in Jialin according to the characteristics of the production process of D. mellonella. , digitalis, chlorophyll and other products. The relevant production methods and experiences are now described below: