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目的:分析急性高血糖脑卒中抑郁患者的特点,并探究其临床转归情况。方法:从我院接收的急性高血糖脑卒中患者中抽选出92例作为本次研究的分析对象,其中,46例为急性高血糖脑卒中抑郁患者(观察组),其余46例为普通高血糖脑卒中患者(对照组)。患者入院后,分别观察其临床症状的差异情况,并采用日常生活能力评定(ADL)与简明智能量表(MMSE)分别评价两组患者的日常生活能力与认知功能情况。给予两组患者相同的急性高血糖脑卒中治疗方案,且比较两组患者治疗前后的脑卒中神经功能缺损以及相应的临床转归情况。结果:与对照组相比,观察组存在明显的情绪低落、焦虑、食欲减退、失眠或睡眠倒错等临床症状,其ADL评分明显高于对照组(t=3.27,P<0.05);MMSE评分明显高于对照组(t=5.38,P<0.05)。观察组患者的神经功能缺损评分下降幅度较小,且痊愈率、缠绵率明显高于对照组的对应值;其死亡率、后遗率明显低于对照组(χ~2=15.525;P<0.05)。结论:与急性高血糖脑卒中相比,急性高血糖脑卒中抑郁患者的疾病情况更加严重,治疗治疗过程中,其经功能缺损情况恢复速率较为缓慢,且临床转归情况不甚理想。
Objective: To analyze the characteristics of depression in patients with acute hyperglycemia and to explore the clinical outcome. Methods: A total of 92 patients with acute hyperglycemic stroke admitted to our hospital were enrolled in this study. Among them, 46 were patients with acute hypoglycemic stroke (observation group), and the remaining 46 patients were normal high Blood sugar stroke patients (control group). After admission, the differences of clinical symptoms were observed. ADL and MMSE were used to evaluate the daily living ability and cognitive function of the two groups. Patients in both groups were given the same treatment program of acute hyperglycemic stroke, and the neurological deficits in stroke and corresponding clinical outcomes were compared between the two groups before and after treatment. Results: Compared with the control group, the ADL score of the observation group was significantly higher than that of the control group (t = 3.27, P <0.05); the scores of MMSE Significantly higher than the control group (t = 5.38, P <0.05). The decline of neurological deficit score in the observation group was smaller, and the recovery rate and the rate of lodging were significantly higher than that of the control group. The mortality and the success rate were significantly lower than those in the control group (χ ~ 2 = 15.525; P <0.05 ). CONCLUSION: Compared with acute hyperglycemic stroke, the patients with acute hyperglycemia, stroke and depression are even more aggravated. During the treatment and treatment, the recovery rate of functional impairment is relatively slow, and the clinical outcome is not satisfactory.