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目的研究分析食管癌患者术后感染病原菌的耐药性,为治疗食管癌术后感染提供依据。方法选取2011年9月-2014年11月医院收治的235例食管癌术后感染患者,统计分析感染患者病原菌种类及其耐药性,采用SPSS18.0软件对数据进行统计分析。结果共分离出病原菌312株,其中革兰阴性菌254株占81.41%,革兰阳性菌37株占11.86%,真菌21株占6.73%;革兰阴性菌对头孢曲松、美洛西林、环丙沙星的耐药率较高,均>50.00%,对亚胺培南的耐药率较低,<33.00%;革兰阳性菌对苯唑西林、青霉素、阿奇霉素、头孢唑林及环丙沙星的耐药率较高,均>50.00%,对万古霉素均较敏感,耐药率为0。结论食管癌患者术后感染的耐药菌以革兰阴性菌为主,临床应根据耐药菌的耐药性及特点,给予相应的治疗。
Objective To study the drug resistance of pathogenic bacteria in patients with esophageal cancer after operation and provide the basis for postoperative infection of esophageal cancer. Methods Totally 235 patients with postoperative esophageal cancer who were admitted to our hospital from September 2011 to November 2014 were enrolled in this study. The types of pathogens and drug resistance were analyzed statistically. The data were analyzed by SPSS18.0 software. Results A total of 312 pathogenic bacteria were isolated, of which, 254 strains of Gram-negative bacteria accounted for 81.41%, 37 strains of Gram-positive bacteria accounted for 11.86% and 21 strains accounted for 6.73%. Gram-negative bacteria were negative for ceftriaxone, mezlocillin, Ciprofloxacin resistant rate was higher, were> 50.00%, resistance to imipenem was low, <33.00%; Gram-positive bacteria on oxacillin, penicillin, azithromycin, cefazolin and cyclopropane The rate of drug resistance of the sand star is higher, both> 50.00%, are more sensitive to vancomycin, drug resistance rate of 0. Conclusion The patients with esophageal cancer infection after the drug-resistant bacteria to Gram-negative bacteria, clinical should be based on resistance to drug-resistant bacteria and characteristics, given the appropriate treatment.