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目的探讨晨尿与随机尿微量白蛋白尿肌酐比值检查对早期糖尿病肾病患者的临床意义。方法应用全自动生化分析仪分别对108例2型糖尿病早期肾病患者的晨尿及随机尿中微量白蛋白与肌酐的含量进行检测后计算比值,比较患者的晨尿与随机尿微量白蛋白尿肌酐比值有无差别,并与24h尿微量白蛋白排泄率做相关性分析。结果晨尿与随机尿微量白蛋白与肌酐的比值结果无统计学差异(p>0.05),与24h尿微量白蛋白排泄率呈正相关。结论随机尿和晨尿尿样标本留取简单,尿微量白蛋白尿肌酐比值检验结果可靠,可替代24h尿白蛋白定量检测用于糖尿病肾病的早期诊断。
Objective To investigate the clinical significance of morning urine and random urine microalbuminuria creatinine ratio in patients with early diabetic nephropathy. Methods The urine samples were collected from 108 patients with type 2 diabetes mellitus with early nephropathy and the urinary microalbumin and creatinine were detected by automatic biochemical analyzer. The ratios of morning urine and random urine microalbuminuria Whether the ratio of difference, and with 24h urinary albumin excretion rate do correlation analysis. Results The results of morning urine and random urine microalbumin to creatinine showed no significant difference (p> 0.05), and had a positive correlation with 24h urinary albumin excretion rate. Conclusion Random urine and morning urine samples are simple to take, urine microalbuminuria creatinine test results are reliable and can replace 24 hours urinary albumin quantitative detection of early diagnosis of diabetic nephropathy.