代谢综合征的常见临床表现是血脂异常、肥胖、高血压以及血糖损害等等,但是由于对于它们的共同的分子机制了解有限,因而也阻碍了对整体治疗方法的研究。在对治疗药物的研究中已经出现了一系列和能量平衡调节相关的动物模型。做为模型重要的一部分,胃肠激素ghrelin被认为是一个能够向大脑报告机体能量状态的分子,它可以增加脂肪合成、升高血压 Common clinical manifestations of metabolic syndrome are dyslipidemia, obesity, hypertension, and impaired glucose tolerance, but the limited understanding of their common molecular mechanisms also hinders the study of holistic therapies. A series of animal models related to energy balance regulation have emerged in the study of therapeutic drugs. As an important part of the model, the ghrelin, a gastrointestinal hormone, is thought to be a molecule that reports to the brain the energy status of the body that increases fat synthesis and blood pressure